Literature summary for 1.3.1.22 extracted from

Beckmann, M.W.; Wieacker, P.; Dereser, M.M.; Flecken, U.; Breckwoldt, M.
Influence of steroid hormones on 5alpha-reductase activity in female and male genital skin fibroblats in culture (1993), Acta Endocrinol., 128, 161-167.

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Activating Compound

Activating Compound	Comment	Organism	Structure
androstandione	in male foreskin fibroblasts	Homo sapiens
androstenedione	in male foreskin fibroblasts	Homo sapiens
testosterone	in female genital skin fibroblasts	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
estradiol	in female genital skin fibroblasts	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
fibroblast	cultured female and male genital skin fibroblasts	Homo sapiens	-

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Release 2023.1 (January 2023)