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Literature summary for 1.3.1.22 extracted from
- Interferences of zearalenone, zearalanol or estradiol-17beta with the steroid-metabolizing enzymes of the human prostate gland (1980), J. Steroid Biochem., 13, 1337-1345.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| estradiol-17beta | - |
Homo sapiens |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| additional information | - |
additional information | variations of Km with various concentrations of zearaleone, zearalanol or estradiol-17beta | Homo sapiens | |
| 0.00073 | - |
testosterone | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| prostate gland | hyperplastic | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| cholest-4-en-3-one + NADPH | - |
Homo sapiens | 5-alpha-cholestan-3-one + NADP+ | - |
? | |
| testosterone + NADPH + H+ | - |
Homo sapiens | 17beta-hydroxy-5alpha-androstan-3-one + NADP+ | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADPH | - |
Homo sapiens | |
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