Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
membrane | - |
Tetrahymena thermophila | 16020 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Tetrahymena thermophila | I7ML19 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholesterol + NADP+ | - |
Tetrahymena thermophila | cholesta-5,7-dien-3-beta-ol + NADPH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Des7 | - |
Tetrahymena thermophila |
General Information | Comment | Organism |
---|---|---|
physiological function | a knock out strain shows no differences in growth rates nor cell shape, neither in the presence nor in the absence of added sterols.Sterols found in wild-type are 83.44% cholesta-5,7,22-trien-3beta-ol as the major derivative, besides cholesterol itself, 0.55% cholesta-5,7-dien-3beta-ol and 3.84% cholesta-5,22-dien-3beta-ol. In contrast, in the KODES7 cell line, the only conversion product recovered is 92.76% 22-dehydrocholesterol | Tetrahymena thermophila |