Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1-[p-(beta-Diethylaminoethoxy) phenyl]1-(p-tolyl)-2-(p-chlorophenyl)ethanol | i.e. MER-29 or triparanol | Rattus norvegicus | |
trans-1,4-Bis-(2-chlorobenzylaminomethyl)cyclohexane dihydrochloride | i.e. AY-9944, hypercholesterolaemic drug | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | 105000 x g fraction supernatant | Rattus norvegicus | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholesta-5,7-dien-3-beta-ol + NADPH | Rattus norvegicus | cholesterol biosynthesis | cholesterol + NADP+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partially | Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
cholesta-5,7-dien-3-beta-ol + NADPH | cholesterol biosynthesis | Rattus norvegicus | cholesterol + NADP+ | - |
? | |
cholesta-5,7-dien-3beta-ol + NADPH | - |
Rattus norvegicus | cholesterol + NADP+ | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADPH | - |
Rattus norvegicus |