Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Hg2+ | complete inhibition of both orotate reductase and NADH oxidase reaction | Bifidobacterium bifidum | |
KCN | complete inhibition of orotate reductase reaction | Bifidobacterium bifidum | |
p-chloromercuribenzoate | complete inhibition of both orotate reductase and NADH oxidase reaction | Bifidobacterium bifidum | |
Quinacrine | 19.2% inhibition of orotate reductase reaction | Bifidobacterium bifidum |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
130000 | - |
gel filtration | Bifidobacterium bifidum |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bifidobacterium bifidum | B7X933 | subunit PyrDb; bifunctional orotate reductase and H2O2-forming NADH oxidase | - |
Purification (Comment) | Organism |
---|---|
- |
Bifidobacterium bifidum |
Subunits | Comment | Organism |
---|---|---|
tetramer | 2 * subunit PyrDb plus 2 * subunit PyrK | Bifidobacterium bifidum |
Synonyms | Comment | Organism |
---|---|---|
b-type dihydroorotate dehydrogenase | - |
Bifidobacterium bifidum |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
and 7.5, NADH oxidase reaction | Bifidobacterium bifidum |
7.5 | - |
and 6.5, NADH oxidase reaction and dihydrorotate oxidase reaction | Bifidobacterium bifidum |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
70% of maximal activity, dihydrorotate oxidase reaction | Bifidobacterium bifidum |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Bifidobacterium bifidum | |
FMN | - |
Bifidobacterium bifidum |