Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus nidulans | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
N-[(5S)-5-amino-5-carboxypentanoyl]-L-cysteinyl-D-valine + O2 = isopenicillin N + 2 H2O | the hydroperoxide-ferrous intermediate, formed by O2-activated H atom abstraction from the substrate, can exploit different reaction pathways and interactions with the substrate govern the final pathway | Aspergillus nidulans |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-alpha-hydroxyisovaleryl ester + O2 | for this substrate analogue (ACOV) lacking an amide nitrogen IPNS exhibits oxygenase activity | Aspergillus nidulans | ? | - |
? | |
delta-L-alpha-aminoadipoyl-L-cysteinyl-D-valine + O2 | for the native substrate IPNS shows oxidase activity | Aspergillus nidulans | isopenicillin N + 2 H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
IPNS | - |
Aspergillus nidulans |
isopenicillin N synthase | - |
Aspergillus nidulans |