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Literature summary for 1.21.3.1 extracted from

  • Gidijala, L.; Bovenberg, R.A.; Klaassen, P.; van der Klei, I.J.; Veenhuis, M.; Kiel, J.A.
    Production of functionally active Penicillium chrysogenum isopenicillin N synthase in the yeast Hansenula polymorpha (2008), BMC Biotechnol., 8, 29.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.21.3.1

Cloned(Commentary)

Cloned (Comment) Organism
functional expression in the cytosol of yeast Hansenula polymorpha, best at 25°C or 30°C growth temperature, at 37°C the recombinant protein is not stable, optimization of culture conditions, overview Penicillium chrysogenum

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Penicillium chrysogenum 5829
-
microbody
-
 Penicillium chrysogenum 42579
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Penicillium chrysogenum in Penicillium chrysogenum, the enzymes involved in penicillin production are compartmentalized in the cytosol and in microbodies ?
-
 ?

Organism

Organism UniProt Comment Textmining
Penicillium chrysogenum
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information in Penicillium chrysogenum, the enzymes involved in penicillin production are compartmentalized in the cytosol and in microbodies Penicillium chrysogenum ?
-
 ?

Synonyms

Synonyms Comment Organism
IPNS
-
 Penicillium chrysogenum
More isopenicillin N synthase belongs to a class of non-heme ferrous iron dependent oxidoreductases Penicillium chrysogenum