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Literature summary for 1.2.1.3 extracted from

  • Giebultowicz, J.; Wolinowska, R.; Sztybor, A.; Pietrzak, M.; Wroczy?ski, P.; Wierzchowski, J.
    Salivary aldehyde dehydrogenase: activity towards aromatic aldehydes and comparison with recombinant ALDH3A1 (2009), Molecules, 14, 2363-2372.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.1.3

Cloned(Commentary)

Cloned (Comment) Organism
into the vector pET28a for expression in Escherichia coli BL21DE3 cells Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.00016
-
 6-methoxy-2-naphthaldehyde recombinant ALDH3A1 Homo sapiens
0.0002
-
 6-methoxy-2-naphthaldehyde salivary ALDH Homo sapiens
0.0004
-
 2-naphthaldehyde recombinant ALDH3A1 Homo sapiens
0.00046
-
 2-naphthaldehyde salivary ALDH Homo sapiens
0.0042
-
 4-Dimethylaminobenzaldehyde recombinant ALDH3A1 Homo sapiens
0.006
-
 cinnamic aldehyde recombinant ALDH3A1 Homo sapiens
0.0072
-
 6-dimethylamino-2-naphthaldehyde salivary ALDH Homo sapiens
0.019
-
 4-methoxybenzaldehyde recombinant ALDH3A1 Homo sapiens
0.02
-
 6-dimethylamino-2-naphthaldehyde recombinant ALDH3A1 Homo sapiens
0.148
-
 benzaldehyde recombinant ALDH3A1 Homo sapiens
0.155
-
 4-hydroxy-3-methoxybenzaldehyde recombinant ALDH3A1 Homo sapiens
0.16
-
 benzaldehyde salivary ALDH Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
52000
-
 determined by SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant ALDH3A1 is isolated with Ni-NTA Fast Start Kit Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
cornea
-
 Homo sapiens
-
lung
-
 Homo sapiens
-
saliva
-
 Homo sapiens
-
stomach
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-naphthaldehyde + NAD+ + H2O
-
 Homo sapiens 1-naphthoic acid + NADH + H+
-
 ?
2-naphthaldehyde + NAD+ + H2O
-
 Homo sapiens 2-naphthoic acid + NADH + H+
-
 ?
4-dimethylamino-1-naphthaldehyde + NAD+ + H2O
-
 Homo sapiens 4-dimethylamino-1-naphthoic acid + NADH + H+
-
 ?
4-dimethylaminobenzaldehyde + NAD+ + H2O
-
 Homo sapiens 4-dimethylaminobenzoate + NADH + H+
-
 ?
4-hydroxy-3-methoxybenzaldehyde + NAD+ + H2O
-
 Homo sapiens 4-hydroxy-3-methoxybenzoate + NADH + H+
-
 ?
4-methoxy-1-naphthaldehyde + NAD+ + H2O
-
 Homo sapiens 4-methoxy-1-naphthoic acid + NADH + H+
-
 ?
4-methoxybenzaldehyde + NAD+ + H2O
-
 Homo sapiens 4-methoxybenzoate + NADH + H+
-
 ?
6-dimethylamino-2-naphthaldehyde + NAD+ + H2O
-
 Homo sapiens 6-dimethylamino-2-naphthoic acid + NADH + H+
-
 ?
6-methoxy-2-naphthaldehyde + NAD+ + H2O
-
 Homo sapiens 6-methoxy-2-naphthoic acid + NADH + H+
-
 ?
7-methoxy-1-naphthaldehyde + NAD+ + H2O
-
 Homo sapiens 7-methoxy-1-naphthoic acid + NADH + H+
-
 ?
benzaldehyde + NAD+ + H2O
-
 Homo sapiens benzoate + NADH + H+
-
 ?
cinnamic aldehyde + NAD+ + H2O
-
 Homo sapiens cinnamic acid + NADH + H+
-
 ?

Subunits

Subunits Comment Organism
homodimer
-
 Homo sapiens

Synonyms

Synonyms Comment Organism
aldehyde dehydrogenase
-
 Homo sapiens
ALDH3A1
-
 Homo sapiens
sALDH
-
 Homo sapiens
salvery aldehyde dehydrogenase
-
 Homo sapiens

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 activity assay Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.5
-
 activity assay Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Homo sapiens