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Literature summary for 1.2.1.3 extracted from

  • Brodeur, H.; Parisotto, M.; Chagnon, S.; Mader, S.; Bhat, P.V.
    Isomer-specific retinoic acid biosynthesis in HeLa cells expressing recombinant class I aldehyde dehydrogenases (2007), Biochim. Biophys. Acta, 1770, 1548-1556.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HeLa, Hep-G2 and JTC-12 cells Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
retina
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
9-cis retinal + NAD+ + H2O
-
Homo sapiens 9-cis retinoic acid + NADH
-
?
all-trans retinal + NAD+ + H2O
-
Homo sapiens all-trans retinoic acid + NADH
-
?

Synonyms

Synonyms Comment Organism
ALDH1
-
Homo sapiens
class 1 aldehyde dehydrogenase
-
Homo sapiens
RalDH1
-
Homo sapiens
retinal dehydrogenase type I
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Homo sapiens