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Literature summary for 1.2.1.3 extracted from

  • Lassen, N.; Estey, T.; Tanguay, R.L.; Pappa, A.; Reimers, M.J.; Vasiliou, V.
    Molecular cloning, baculovirus expression, and tissue distribution of the zebrafish aldehyde dehydrogenase 2 (2005), Drug Metab. Dispos., 33, 649-656.
    View publication on PubMed
Search for more literature for 1.2.1.3

Activating Compound

Activating Compound Comment Organism Structure
2-mercaptoethanol highest activity at 50 mM Danio rerio
2-mercaptoethanol highest activity at 50 mM Homo sapiens

Cloned(Commentary)

Cloned (Comment) Organism
expression in Spodoptera frugiperda cells Danio rerio
expression in Spodoptera frugiperda cells Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0024
-
 propanal 0.1 M sodium diphosphate pH 8.0, 1 mM NAD+, 50 mM 2-mercaptoethanol, 1 mM pyrazole, 30 min, 25°C Homo sapiens
0.0032
-
 acetaldehyde 0.1 M sodium diphosphate pH 8.0, 1 mM NAD+, 50 mM 2-mercaptoethanol, 1 mM pyrazole, 30 min, 25°C Homo sapiens
0.0061
-
 propanal 0.1 M sodium diphosphate pH 8.0, 1 mM NAD+, 50 mM 2-mercaptoethanol, 1 mM pyrazole, 30 min, 25°C Danio rerio
0.0115
-
 acetaldehyde 0.1 M sodium diphosphate pH 8.0, 1 mM NAD+, 50 mM 2-mercaptoethanol, 1 mM pyrazole, 30 min, 25°C Danio rerio

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
56000
-
 SDS-PAGE Danio rerio
56000
-
 SDS-PAGE Homo sapiens

Organism

Organism UniProt Comment Textmining
Danio rerio
-
-
-
Homo sapiens P05091
-
-

Purification (Commentary)

Purification (Comment) Organism
5'-AMP-Sepharose 4B affinity column, 95% purity Danio rerio
5'-AMP-Sepharose 4B affinity column, 95% purity Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
brain highly expressed Danio rerio
-
eye expressed Danio rerio
-
heart highly expressed Danio rerio
-
liver expressed Danio rerio
-
skeletal muscle highly expressed Danio rerio
-
swim bladder expressed Danio rerio
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetaldehyde + NAD+ + H2O
-
 Danio rerio acetate + NADH + H+
-
 ?
acetaldehyde + NAD+ + H2O
-
 Homo sapiens acetate + NADH + H+
-
 ?
propanal + NAD+ + H2O
-
 Danio rerio propionate + NADH
-
 ?
propanal + NAD+ + H2O
-
 Homo sapiens propionate + NADH
-
 ?

Synonyms

Synonyms Comment Organism
aldehyde dehydrogenase
-
 Danio rerio
aldehyde dehydrogenase
-
 Homo sapiens
ALDH2
-
 Danio rerio
ALDH2
-
 Homo sapiens