Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.2.1.3 extracted from

  • Sladek, N.E.
    Human aldehyde dehydrogenases: Potential pathological, pharmacological, and toxicological impact (2003), J. Biochem. Mol. Toxicol., 17, 7-23.
    View publication on PubMed
Search for more literature for 1.2.1.3

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Homo sapiens 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
54400
-
 4 * 54400 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-
heart
-
 Homo sapiens
-
kidney tissue with highest content Homo sapiens
-
lens tissue with highest content Homo sapiens
-
liver tissue with highest content Homo sapiens
-
lung
-
 Homo sapiens
-
pancreas
-
 Homo sapiens
-
prostate gland
-
 Homo sapiens
-
skeletal muscle
-
 Homo sapiens
-
spleen
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetaldehyde + NAD+ + H2O preferred substrate Homo sapiens acetate + NADH + H+
-
 ?
chloroacetaldehyde + NAD+ + H2O
-
 Homo sapiens chloroacetate + NADH + H+
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 54400 Homo sapiens

Synonyms

Synonyms Comment Organism
ALDH 2
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Homo sapiens

pI Value

Organism Comment pI Value Maximum pI Value
Homo sapiens about
-
 4.9