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Literature summary for 1.2.1.3 extracted from
- Purification and properties of a membrane-bound aldehyde dehydrogenase from rat liver microsomes (1978), Biochem. Biophys. Res. Commun., 83, 697-703.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | membrane-bound | Rattus norvegicus | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 51000 | - |
x * 51000, exists as large polymeric aggregates, SDS-PAGE | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Rattus norvegicus | the microsomal membrane-bound enzyme is expected to catalyze the oxidation of such water-insoluble aldehydes produced on the surface of the microsomal membrane. The enzyme may also be involved in the conversion of fatty acids to alpha,omega-dicarboxylic acids | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 20.29 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| decanal + NAD+ + H2O | - |
Rattus norvegicus | decanoate + NADH | - |
? | |
| additional information | the microsomal membrane-bound enzyme is expected to catalyze the oxidation of such water-insoluble aldehydes produced on the surface of the microsomal membrane. The enzyme may also be involved in the conversion of fatty acids to alpha,omega-dicarboxylic acids | Rattus norvegicus | ? | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 51000, exists as large polymeric aggregates, SDS-PAGE | Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NAD+ | - |
Rattus norvegicus | |
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