Application | Comment | Organism |
---|---|---|
medicine | the Porphyromonas gingivalis client proteins tonB-dependent receptor protein RagA4, 4-hydroxybutyryl-coenzyme A dehydratase AbfD, GAPDH, NAD-dependent glutamate dehydrogenase GDH, and malate dehydrogenase MDH function as regulators in Porphyromonas gingivalis biofilm formation with oral streptococci | Streptococcus oralis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glyceraldehyde 3-phosphate + phosphate + NAD+ | Streptococcus oralis | - |
3-phospho-D-glyceroyl phosphate + NADH + H+ | - |
? | |
D-glyceraldehyde 3-phosphate + phosphate + NAD+ | Streptococcus oralis ATCC 9811 | - |
3-phospho-D-glyceroyl phosphate + NADH + H+ | - |
? | |
additional information | Streptococcus oralis | Streptococcus oralis glyceraldehyde-3-phosphate dehydrogenase shows high affinity for tonB-dependent receptor protein RagA4, arginine-specific proteinase B, 4-hydroxybutyryl-coenzyme A dehydratase, glyceraldehyde-3-phosphate dehydrogenase, NAD-dependent glutamate dehydrogenase, and malate dehydrogenase from Porphyromonas gingivalis which function as regulators in biofilm formation with oral streptococci | ? | - |
? | |
additional information | Streptococcus oralis ATCC 9811 | Streptococcus oralis glyceraldehyde-3-phosphate dehydrogenase shows high affinity for tonB-dependent receptor protein RagA4, arginine-specific proteinase B, 4-hydroxybutyryl-coenzyme A dehydratase, glyceraldehyde-3-phosphate dehydrogenase, NAD-dependent glutamate dehydrogenase, and malate dehydrogenase from Porphyromonas gingivalis which function as regulators in biofilm formation with oral streptococci | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptococcus oralis | - |
- |
- |
Streptococcus oralis | Q76BL9 | ATCC 9811 | - |
Streptococcus oralis ATCC 9811 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glyceraldehyde 3-phosphate + phosphate + NAD+ | - |
Streptococcus oralis | 3-phospho-D-glyceroyl phosphate + NADH + H+ | - |
? | |
D-glyceraldehyde 3-phosphate + phosphate + NAD+ | - |
Streptococcus oralis ATCC 9811 | 3-phospho-D-glyceroyl phosphate + NADH + H+ | - |
? | |
additional information | Streptococcus oralis glyceraldehyde-3-phosphate dehydrogenase shows high affinity for tonB-dependent receptor protein RagA4, arginine-specific proteinase B, 4-hydroxybutyryl-coenzyme A dehydratase, glyceraldehyde-3-phosphate dehydrogenase, NAD-dependent glutamate dehydrogenase, and malate dehydrogenase from Porphyromonas gingivalis which function as regulators in biofilm formation with oral streptococci | Streptococcus oralis | ? | - |
? | |
additional information | Streptococcus oralis glyceraldehyde-3-phosphate dehydrogenase shows high affinity for tonB-dependent receptor protein RagA4, arginine-specific proteinase B, 4-hydroxybutyryl-coenzyme A dehydratase, glyceraldehyde-3-phosphate dehydrogenase, NAD-dependent glutamate dehydrogenase, and malate dehydrogenase from Porphyromonas gingivalis which function as regulators in biofilm formation with oral streptococci | Streptococcus oralis ATCC 9811 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
GAPDH | - |
Streptococcus oralis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Streptococcus oralis |
General Information | Comment | Organism |
---|---|---|
physiological function | enzyme shows high affinity for Porphyromonas gingivalis proteins tonB-dependent receptor protein RagA4, 4-hydroxybutyryl-coenzyme A dehydratase AbfD, GAPDH, NAD-dependent glutamate dehydrogenase GDH, and malate dehydrogenase MDH. tonB-Dependent receptor protein RagA4, 4-hydroxybutyryl-coenzyme A dehydratase AbfD and NAD-dependent glutamate dehydrogenase GDH enhance coaggregation, whereas GAPDH and malate dehydrogenase inhibite coaggregation | Streptococcus oralis |