Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.2.1.12 extracted from

  • Maeda, K.; Nagata, H.; Kuboniwa, M.; Ojima, M.; Osaki, T.; Minamino, N.; Amano, A.
    Identification and characterization of Porphyromonas gingivalis client proteins that bind to Streptococcus oralis glyceraldehyde-3-phosphate dehydrogenase (2013), Infect. Immun., 81, 753-763.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.1.12

Application

Application Comment Organism
medicine the Porphyromonas gingivalis client proteins tonB-dependent receptor protein RagA4, 4-hydroxybutyryl-coenzyme A dehydratase AbfD, GAPDH, NAD-dependent glutamate dehydrogenase GDH, and malate dehydrogenase MDH function as regulators in Porphyromonas gingivalis biofilm formation with oral streptococci Streptococcus oralis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-glyceraldehyde 3-phosphate + phosphate + NAD+ Streptococcus oralis
-
 3-phospho-D-glyceroyl phosphate + NADH + H+
-
 ?
D-glyceraldehyde 3-phosphate + phosphate + NAD+ Streptococcus oralis ATCC 9811
-
 3-phospho-D-glyceroyl phosphate + NADH + H+
-
 ?
additional information Streptococcus oralis Streptococcus oralis glyceraldehyde-3-phosphate dehydrogenase shows high affinity for tonB-dependent receptor protein RagA4, arginine-specific proteinase B, 4-hydroxybutyryl-coenzyme A dehydratase, glyceraldehyde-3-phosphate dehydrogenase, NAD-dependent glutamate dehydrogenase, and malate dehydrogenase from Porphyromonas gingivalis which function as regulators in biofilm formation with oral streptococci ?
-
 ?
additional information Streptococcus oralis ATCC 9811 Streptococcus oralis glyceraldehyde-3-phosphate dehydrogenase shows high affinity for tonB-dependent receptor protein RagA4, arginine-specific proteinase B, 4-hydroxybutyryl-coenzyme A dehydratase, glyceraldehyde-3-phosphate dehydrogenase, NAD-dependent glutamate dehydrogenase, and malate dehydrogenase from Porphyromonas gingivalis which function as regulators in biofilm formation with oral streptococci ?
-
 ?

Organism

Organism UniProt Comment Textmining
Streptococcus oralis
-
-
-
Streptococcus oralis Q76BL9 ATCC 9811
-
Streptococcus oralis ATCC 9811
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-glyceraldehyde 3-phosphate + phosphate + NAD+
-
 Streptococcus oralis 3-phospho-D-glyceroyl phosphate + NADH + H+
-
 ?
D-glyceraldehyde 3-phosphate + phosphate + NAD+
-
 Streptococcus oralis ATCC 9811 3-phospho-D-glyceroyl phosphate + NADH + H+
-
 ?
additional information Streptococcus oralis glyceraldehyde-3-phosphate dehydrogenase shows high affinity for tonB-dependent receptor protein RagA4, arginine-specific proteinase B, 4-hydroxybutyryl-coenzyme A dehydratase, glyceraldehyde-3-phosphate dehydrogenase, NAD-dependent glutamate dehydrogenase, and malate dehydrogenase from Porphyromonas gingivalis which function as regulators in biofilm formation with oral streptococci Streptococcus oralis ?
-
 ?
additional information Streptococcus oralis glyceraldehyde-3-phosphate dehydrogenase shows high affinity for tonB-dependent receptor protein RagA4, arginine-specific proteinase B, 4-hydroxybutyryl-coenzyme A dehydratase, glyceraldehyde-3-phosphate dehydrogenase, NAD-dependent glutamate dehydrogenase, and malate dehydrogenase from Porphyromonas gingivalis which function as regulators in biofilm formation with oral streptococci Streptococcus oralis ATCC 9811 ?
-
 ?

Synonyms

Synonyms Comment Organism
GAPDH
-
 Streptococcus oralis

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Streptococcus oralis

General Information

General Information Comment Organism
physiological function enzyme shows high affinity for Porphyromonas gingivalis proteins tonB-dependent receptor protein RagA4, 4-hydroxybutyryl-coenzyme A dehydratase AbfD, GAPDH, NAD-dependent glutamate dehydrogenase GDH, and malate dehydrogenase MDH. tonB-Dependent receptor protein RagA4, 4-hydroxybutyryl-coenzyme A dehydratase AbfD and NAD-dependent glutamate dehydrogenase GDH enhance coaggregation, whereas GAPDH and malate dehydrogenase inhibite coaggregation Streptococcus oralis