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Literature summary for 1.2.1.12 extracted from

  • Yang, S.; Liu, M.; Tien, C.; Chou, S.; Chang, R.
    Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) interaction with 3 ends of Japanese encephalitis virus RNA and colocalization with the viral NS5 protein (2009), J. Biomed. Sci., 16, 40.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.2.1.12

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol GAPDH colocalizes with viral RNA-dependentRNA polymerase in cells infected with Japanese encephalitis virus. GAPDH remains relatively constant in the cytosol, while increasing at 12 to 24 hours postinfection and decreasing at 36 hours postinfection in the nuclear fraction of infected cells. There is no direct protein-protein interaction; instead, GAPDH binds to the 3' termini of plus- and minus-strand RNAs of Japanese encephalitis virus. GAPDH binds to the minus-strand more efficiently than to the plus-strand of Japanese encephalitis virus RNAs Homo sapiens 5829
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cytosol GAPDH colocalizes with viral RNA-dependentRNA polymerase in cells infected with Japanese encephalitis virus. GAPDH remains relatively constant in the cytosol, while increasing at 12 to 24 hours postinfection and decreasing at 36 hours postinfection in the nuclear fraction of infected cells. There is no direct protein-protein interaction; instead, GAPDH binds to the 3' termini of plus- and minus-strand RNAs of Japanese encephalitis virus. GAPDH binds to the minus-strand more efficiently than to the plus-strand of Japanese encephalitis virus RNAs Mesocricetus auratus 5829
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nucleus GAPDH colocalizes with viral RNA-dependentRNA polymerase in cells infected with Japanese encephalitis virus. GAPDH remains relatively constant in the cytosol, while increasing at 12 to 24 hours postinfection and decreasing at 36 hours postinfection in the nuclear fraction of infected cells. There is no direct protein-protein interaction; instead, GAPDH binds to the 3' termini of plus- and minus-strand RNAs of Japanese encephalitis virus. GAPDH binds to the minus-strand more efficiently than to the plus-strand of Japanese encephalitis virus RNAs Homo sapiens 5634
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nucleus GAPDH colocalizes with viral RNA-dependentRNA polymerase in cells infected with Japanese encephalitis virus. GAPDH remains relatively constant in the cytosol, while increasing at 12 to 24 hours postinfection and decreasing at 36 hours postinfection in the nuclear fraction of infected cells. There is no direct protein-protein interaction; instead, GAPDH binds to the 3' termini of plus- and minus-strand RNAs of Japanese encephalitis virus. GAPDH binds to the minus-strand more efficiently than to the plus-strand of Japanese encephalitis virus RNAs Mesocricetus auratus 5634
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Mesocricetus auratus
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Source Tissue

Source Tissue Comment Organism Textmining
BHK-21 cell infected with Japanese encephalitis virus Mesocricetus auratus
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HEK-293 cell infected with Japanese encephalitis virus Homo sapiens
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