Cloned (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Crystallization (Comment) | Organism |
---|---|
structure determination by formation of soluble recombinant rat sperm glyceraldehyde-3-phosphate dehydrogenase as a heterotetramer with the Escherichia coli glyceraldehyde-3-phosphate dehydrogenase in a ratio of 1:3. Glyceraldehyde 3-phosphate binds in the Ps pocket in the active site of the sperm enzyme subunit in the presence of NAD | Escherichia coli |
structure determination by formation of soluble recombinant rat sperm glyceraldehyde-3-phosphate dehydrogenase as a heterotetramer with the Escherichia coli glyceraldehyde-3-phosphate dehydrogenase in a ratio of 1:3. Refinement to 2.2 A for the holo enzyme, to 2.4 A for the complex with glyceraldehyde 3-phosphate. Glyceraldehyde 3-phosphate binds in the Ps pocket in the active site of the sperm enzyme subunit in the presence of NAD | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
alpha-chlorohydrin | the contraceptive activity of alpha-chlorohydrin and its apparent specificity for the sperm isoform in vivo are likely to be due to differences in metabolism to 3-chlorolactaldehyde in spermatozoa and somatic cells | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | P0A9B2 | - |
- |
Rattus norvegicus | Q9ESV6 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
sperm | - |
Rattus norvegicus | - |