Application | Comment | Organism |
---|---|---|
medicine | in transgenic human lung and colon cancer lines expressing xanthine oxidase regulatory subunit RRM1, G2 cell cycle arrest, apoptosis, and efficient DNA damage repair are induced | Homo sapiens |
medicine | in transgenic mice expressing xanthine oxidase regulatory subunit RRM1, carcinogen-induced lung tumor formation is significantly suppressed. RRM1 transgenic animals repair chemically induced DNA damage with greater efficiency than control animals | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P23921 | - |
- |
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
carcinoma cell | lung and colon cancer cell lines | Homo sapiens | - |