Activating Compound | Comment | Organism | Structure |
---|---|---|---|
allopurinol | inhibits xanthine and hypoxanthine oxidation in vivo in intestine and pancreas, but enhances the activity in liver, tissue-dependent effects, overview | Gallus gallus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
allopurinol | inhibits xanthine and hypoxanthine oxidation in vivo in intestine and pancreas, but enhances the activity in liver, tissue-dependent effects, overview | Gallus gallus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
hypoxanthine + NAD+ + H2O | Gallus gallus | - |
xanthine + NADH + H+ | - |
? | |
xanthine + NAD+ + H2O | Gallus gallus | - |
urate + NADH + H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
domesticus, male chicken | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
intestine | - |
Gallus gallus | - |
kidney | - |
Gallus gallus | - |
liver | - |
Gallus gallus | - |
pancreas | - |
Gallus gallus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
tissue-dependent enzyme activity, overview | Gallus gallus |
17.5 | - |
pancreas enzyme with allopurinol at 50 mg/kg body weight | Gallus gallus |
17.8 | - |
pancreas enzyme | Gallus gallus |
25.2 | - |
intestine enzyme with allopurinol at 50 mg/kg body weight | Gallus gallus |
26.6 | - |
intestine enzyme | Gallus gallus |
29.5 | - |
kidney enzyme with allopurinol at 50 mg/kg body weight | Gallus gallus |
49.9 | - |
kidney enzyme | Gallus gallus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
hypoxanthine + NAD+ + H2O | - |
Gallus gallus | xanthine + NADH + H+ | - |
? | |
xanthine + NAD+ + H2O | - |
Gallus gallus | urate + NADH + H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
xanthine oxidoreductase | - |
Gallus gallus |
XOR | - |
Gallus gallus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
41 | - |
assay at | Gallus gallus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.8 | - |
assay at | Gallus gallus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Gallus gallus |