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Literature summary for 1.17.1.4 extracted from
- PD98059 enhanced insulin, cytokine, and growth factor activation of xanthine oxidoreductase in epithelial cells involves STAT3 and the glucocorticoid receptor (2007), J. Cell. Biochem., 101, 1567-1587.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| PD98059 | inhibitor used to block MEK-1/2 kinase, activates the promoter of xanthine oxidoreductase and significantly enhances expression of enzyme induced by insulin, acute phase cytokines, or growth factors | Rattus norvegicus |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| epithelium | lung epithelial cell | Rattus norvegicus | - |
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Release 2023.1 (January 2023)
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