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Literature summary for 1.17.1.4 extracted from
- Physicochemical and kinetic properties of purified sheep's milk xanthine oxidoreductase (2004), J. Dairy Sci., 87, 1580-1584.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.00215 | - |
xanthine | pH 7.2, 25°C | Bos taurus |  |
| 0.00219 | - |
NAD+ | pH 7.2, 25°C | Ovis aries | |
| 0.00252 | - |
NAD+ | pH 7.2, 25°C | Homo sapiens | |
| 0.00274 | - |
NAD+ | pH 7.2, 25°C | Bos taurus | |
| 0.00412 | - |
NAD+ | pH 7.2, 25°C | Capra hircus | |
| 0.00633 | - |
xanthine | pH 7.2, 25°C | Capra hircus | |
| 0.00714 | - |
xanthine | pH 7.2, 25°C | Ovis aries | |
| 0.00774 | - |
xanthine | pH 7.2, 25°C | Homo sapiens | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Molybdenum | 0.18 atoms per subunit | Ovis aries | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 150000 | - |
x * 150000, SDS-PAGE | Ovis aries |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Capra hircus | - |
- |
- |
| Homo sapiens | - |
- |
- |
| Ovis aries | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Ovis aries |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| milk | - |
Homo sapiens | - |
| milk | - |
Bos taurus | - |
| milk | - |
Ovis aries | - |
| milk | - |
Capra hircus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.06 | - |
substrate xanthine, pH 7.2, 25°C | Homo sapiens |
| 0.21 | - |
substrate NAD+, pH 7.2, 25°C | Ovis aries |
| 0.25 | - |
substrate NAD+, pH 7.2, 25°C | Bos taurus |
| 0.27 | - |
substrate NAD+, pH 7.2, 25°C | Capra hircus |
| 0.27 | - |
substrate xanthine, pH 7.2, 25°C | Capra hircus |
| 0.29 | - |
substrate NAD+, pH 7.2, 25°C | Homo sapiens |
| 0.69 | - |
substrate xanthine, pH 7.2, 25°C | Ovis aries |
| 1.83 | - |
substrate xanthine, pH 7.2, 25°C | Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| xanthine + NAD+ + H2O | - |
Homo sapiens | urate + NADH | - |
? | |
| xanthine + NAD+ + H2O | - |
Bos taurus | urate + NADH | - |
? | |
| xanthine + NAD+ + H2O | - |
Ovis aries | urate + NADH | - |
? | |
| xanthine + NAD+ + H2O | - |
Capra hircus | urate + NADH | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| ? | x * 150000, SDS-PAGE | Ovis aries |
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