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Literature summary for 1.15.1.1 extracted from

  • Prabhu, H.R.; Nandini, M.
    Inhibition of selenium dependent glutathione peroxidase and superoxide dismutase in rats by diethyldithiocarbamate: effect of pre-administration of alpha-tocopherol (2007), Indian J. Exp. Biol., 45, 465-468.
    View publication on PubMed
Search for more literature for 1.15.1.1

Activating Compound

Activating Compound Comment Organism Structure
additional information no effect on the enzyme by alpha-tocopherol in absence of diethyldithiocarbamate Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
diethyldithiocarbamate causes decline of the enzyme in various tissues after intraperitoneal injection, alpha-tocopherol feeding prior to application of diethyldithiocarbamate leads to reduced inhibition of the enzyme Rattus norvegicus
additional information no effect on the enzyme by alpha-tocopherol in absence of diethyldithiocarbamate Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
O2.- + H+ Rattus norvegicus the enzyme prevents the inhibition of human CYP3A4, UGT1A6, and P-glycoprotein with halogenated xanthene food dyes, overview O2 + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 male Wistar rats
-

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
O2.- + H+
-
 Rattus norvegicus O2 + H2O2
-
 ?
O2.- + H+ the enzyme prevents the inhibition of human CYP3A4, UGT1A6, and P-glycoprotein with halogenated xanthene food dyes, overview Rattus norvegicus O2 + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
SOD
-
 Rattus norvegicus