Literature summary for 1.15.1.1 extracted from

Wagner, U.G.; Werber, M.M.; Beck, Y.; Hartman, J.R.; Frolow, F.; Sussman, J.L.
Characterization of crystals of genetically engineered human manganese superoxide dismutase (1989), J. Mol. Biol., 206, 787-788.

Search for more literature for 1.15.1.1

Application

Application	Comment	Organism
medicine	potential target for drug design	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
Mn-SOD, expression in Escherichia coli	Homo sapiens

Crystallization (Commentary)

Crystallization (Comment)	Organism
from recombinant Mn-SOD, asymmetric unit, hanging drop technique, room temperature, equilibration of 3-4 mg/ml enzyme in ammonium phosphate, pH 5.9, plus 10% 2-methyl-2,4-pentanediol against 32% 2-methyl-2,4-pentanediol, X-ray analysis	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
22000	-	x * 22000, amino acid sequence determination	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	Mn-SOD	-
Homo sapiens Mn-SOD	-	Mn-SOD	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
O2- + H+	-	Homo sapiens	O2 + H2O2	-	?
O2- + H+	-	Homo sapiens Mn-SOD	O2 + H2O2	-	?

Subunits

Subunits	Comment	Organism
?	x * 22000, amino acid sequence determination	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)