Literature summary for 1.14.99.1 extracted from

Miller, D.B.; Munster, D.; Wasvary, J.S.; Simke, J.P.; Peppard, J.V.; Bowen, B.R.; Marshall, P.J.
The heterologous expression and characterization of human prostaglandin G/H synthase-2 (COX-2) (1994), Biochem. Biophys. Res. Commun., 201, 356-362.

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Inhibitors

Inhibitors	Comment	Organism	Structure
6-methylnaphthylacetic acid	recombinant protein, 50% inhibition at 0.08-0.1 mM	Homo sapiens
BW 755C	recombinant protein, 50% inhibition at 0.01-0.02 mM	Homo sapiens
diclofenac	recombinant protein, 50% inhibition at 0.04 mM	Homo sapiens
etodalac	recombinant protein, 50% inhibition at 0.06-0.07 mM	Homo sapiens
ETYA	recombinant protein, 50% inhibition at 0.015-0.025 mM	Homo sapiens
Ibuprofen	recombinant protein, 50% inhibition at 0.04 mM	Homo sapiens
naproxen	recombinant protein, 50% inhibition at 0.05-0.06 mM	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
fibroblast	-	Homo sapiens	-

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Release 2023.1 (January 2023)