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Literature summary for 1.14.99.1 extracted from

  • Hemler, M.; Lands, W.E.M.
    Purification of the cyclooxygenase that forms prostaglandins. Demonstration of two forms of iron in the holoenzyme (1976), J. Biol. Chem., 251, 5575-5579.
    View publication on PubMed
Search for more literature for 1.14.99.1

Activating Compound

Activating Compound Comment Organism Structure
hemin activates Ovis aries

General Stability

General Stability Organism
diethyldithiocarbamate stabilizes Ovis aries
ethylene glycol stabilizes Ovis aries
flufenamate stabilizes Ovis aries
glycerol stabilizes Ovis aries

Localization

Localization Comment Organism GeneOntology No. Textmining

Metals/Ions

Metals/Ions Comment Organism Structure
Iron possibly contains heme and non-heme iron Ovis aries

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
70000
-
 x * 70000, SDS-PAGE in absence and presence of 2-mercaptoethanol Ovis aries

Organism

Organism UniProt Comment Textmining
Ovis aries
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Ovis aries

Source Tissue

Source Tissue Comment Organism Textmining
seminal vesicle
-
 Ovis aries
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arachidonic acid + AH2 + 2 O2
-
 Ovis aries 15-hydroperoxy-9alpha,11alpha-peroxidoprosta-5,13-dienoic acid + A + H2O
-
 ?

Subunits

Subunits Comment Organism
? x * 70000, SDS-PAGE in absence and presence of 2-mercaptoethanol Ovis aries

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
30
-
 pH 8.0, 5 min, stable Ovis aries

Cofactor

Cofactor Comment Organism Structure
heme enzyme contains a heme group Ovis aries