Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
stearoyl-CoA + NADH + H+ + O2 | - |
Mus musculus | oleoyl-CoA + NAD+ + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SCD1 | - |
Mus musculus |
stearoyl-CoA desaturase-1 | - |
Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADH | - |
Mus musculus |
General Information | Comment | Organism |
---|---|---|
physiological function | absence of stearoyl-CoA desaturase-1 leads to chronic inflammation of the skin and increased susceptibility to atherosclerosis, while also increasing plasma inflammatory markers, but does not promote dextran sulfate sodium-induced acute colitis | Mus musculus |