Any feedback?
Literature summary for 1.14.19.1 extracted from
- Identification and characterization of a novel bovine stearoyl-CoA desaturase isoform with homology to human SCD5 (2007), Lipids, 42, 499-508.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene SCD1, phylogenetic tree, sequence comparisons with other isozymes and enzymes from other organisms, overview | Bos taurus |
| gene SCD5, DNA and amino acid sequence determination and analysis, phylogenetic tree, sequence comparisons with other isozymes and enzymes from other organisms, overview | Bos taurus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| stearoyl-CoA + ferrocytochrome b5 + O2 + H+ | Bos taurus | - |
oleoyl-CoA + ferricytochrome b5 + H2O | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | Q2KIA4 | isozyme SCD5; isozyme SCD5 | - |
| Bos taurus | Q9TT94 | isozyme SCD1; isozyme SCD1 | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| adipose tissue | high expression level of isozyme SCD1 | Bos taurus | - |
| adipose tissue | low expression level of isozyme SCD1 | Bos taurus | - |
| brain | - |
Bos taurus | - |
| brain | specific high expression level of isozyme SCD5, equally distributed between white and gray matter | Bos taurus | - |
| heart | - |
Bos taurus | - |
| heart | low expression level of isozyme SCD1 | Bos taurus | - |
| liver | low expression level of isozyme SCD1 | Bos taurus | - |
| lung | - |
Bos taurus | - |
| additional information | no expression of isozyme SCD5 in lung | Bos taurus | - |
| skeletal muscle | - |
Bos taurus | - |
| skeletal muscle | low expression level of isozyme SCD1 | Bos taurus | - |
| spleen | low expression level of isozyme SCD1 | Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | the enzyme also produces cis-9, trans-11 conjugated linoleic acid and palmitoleoyl-CoA | Bos taurus | ? | - |
? | |
| stearoyl-CoA + ferrocytochrome b5 + O2 + H+ | - |
Bos taurus | oleoyl-CoA + ferricytochrome b5 + H2O | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| SCD | - |
Bos taurus |
| SCD1 | - |
Bos taurus |
| stearoyl-CoA desaturase | - |
Bos taurus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| ferrocytochrome b5 | - |
Bos taurus | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
