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Literature summary for 1.14.19.1 extracted from

  • Flowers, M.T.; Miyazaki, M.; Liu, X.; Ntambi, J.M.
    Probing the role of stearoyl-CoA desaturase-1 in hepatic insulin resistance (2006), J. Clin. Invest., 116, 1478-1481.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Mus musculus
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Source Tissue

Source Tissue Comment Organism Textmining
adipose tissue injection of Scd1 sequence-specific antisense oligodeoxynucleotides decreases Scd1 gene expression in brown and white adipose tissue as well as in liver Mus musculus
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liver injection of Scd1 sequence-specific antisense oligodeoxynucleotides decreases Scd1 gene expression in brown and white adipose tissue as well as in liver Mus musculus
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
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antisense oligodeoxynucleotide-mediated inhibition SCD1 in C57BL/6J mice results in resistance to high-fat diet-induced obesity and hepatic steatosis, also lower levels of postprandial glucose and insulin, increased oxygen consumption, increased physical activity and reduced lipogenic gene expression Mus musculus

Synonyms

Synonyms Comment Organism
SCD1
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Mus musculus