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Literature summary for 1.14.19.1 extracted from

  • Scott, W.; Foote, J.L.
    The inhibition of stearoyl-coenzyme A desaturase by phenyllactate and phenylpyruvate (1979), Biochim. Biophys. Acta, 573, 197-200.
    View publication on PubMed
Search for more literature for 1.14.19.1

Inhibitors

Inhibitors Comment Organism Structure
additional information phenylalanine, indolepyruvic acid and 2-amino-1-phenylethanol show no inhibitory effect Rattus norvegicus
Phenyllactate partial inhibition, maximal at 0.08 mM Rattus norvegicus
phenylpyruvate partial inhibition Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
stearoyl-CoA + AH2 + O2 Rattus norvegicus
-
 oleoyl-CoA + A + H2O
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
 maximal activity at a concentration of 0.03 mM stearoyl-CoA Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ammonium stearate + NADH + O2
-
 Rattus norvegicus ?
-
 ?
stearoyl-CoA + AH2 + O2
-
 Rattus norvegicus oleoyl-CoA + A + H2O
-
 ?
stearoyl-CoA + NADH + O2
-
 Rattus norvegicus oleoyl-CoA + NAD+ + H2O
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.35
-
 assay at Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
NADH
-
 Rattus norvegicus