Inhibitors | Comment | Organism | Structure |
---|---|---|---|
cefazolin | reversible, competitive inhibition of both monophenolase and diphenolase activities of tyrosinase | Agaricus bisporus | |
cefodizime | reversible, mixed-type inhibition of both monophenolase and diphenolase activities of tyrosinase | Agaricus bisporus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tyrosine + O2 | - |
Agaricus bisporus | L-DOPA + H2O | - |
? |
Synonyms | Comment | Organism |
---|---|---|
tyrosinase | - |
Agaricus bisporus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0129 | - |
cefodizime | in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 30°C | Agaricus bisporus | |
0.11 | - |
cefazolin | in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 30°C | Agaricus bisporus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.02 | - |
for diphenolase activity of tyrosinase, in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 30°C | Agaricus bisporus | cefazolin | |
0.13 | - |
for monophenolase activity of tyrosinase, in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 30°C | Agaricus bisporus | cefodizime | |
0.21 | - |
for diphenolase activity of tyrosinase, in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 30°C | Agaricus bisporus | cefodizime | |
7 | - |
for monophenolase activity of tyrosinase, in 50 mM Na2HPO4-NaH2PO4 buffer (pH 6.8), at 30°C | Agaricus bisporus | cefazolin |