Literature summary for 1.14.18.1 extracted from

Leu, Y.L.; Hwang, T.L.; Hu, J.W.; Fang, J.Y.
Anthraquinones from Polygonum cuspidatum as tyrosinase inhibitors for dermal use (2008), Phytother. Res., 22, 552-556.

Search for more literature for 1.14.18.1

Application

Application	Comment	Organism
drug development	commercial plant extracts containing anthraquinones are being increasingly used for pharmaceuticals, foods and cosmetics due to their wide therapeutic and pharmacological properties	Agaricus bisporus

Inhibitors

Inhibitors	Comment	Organism	Structure
anthraglycoside B	anthraquinone, isolated from the root of Polygonum cuspidatum	Agaricus bisporus
citreorosein	anthraquinone, isolated from the root of Polygonum cuspidatum	Agaricus bisporus
emodin	anthraquinone, isolated from the root of Polygonum cuspidatum	Agaricus bisporus
kojic acid	-	Agaricus bisporus
additional information	the ranking of the inhibitory potency is physcion > citreorosein = anthraglycoside B = emodin	Agaricus bisporus
physcion	anthraquinone, isolated from the root of Polygonum cuspidatum. Most potent tyrosinase inhibition among the four anthraquinones examined, which is comparable to kojic acid	Agaricus bisporus

Organism

Organism	UniProt	Comment	Textmining
Agaricus bisporus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
commercial preparation	-	Agaricus bisporus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-dopa + 1/2 O2	-	Agaricus bisporus	L-dopaquinone + H2O	-	?

Synonyms

Synonyms	Comment	Organism
tyrosinase	-	Agaricus bisporus

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Release 2023.1 (January 2023)