Inhibitors | Comment | Organism | Structure |
---|---|---|---|
glycerol | substrate cholesterol, 50% inhibition at 25% glycerol, substrate 22(R)-hydroxycholesterol, 50% inhibition at 44% glycerol, substrate 20alpha-hydroxycholesterol, 50% inhibition at 48% glycerol, substrate 20alpha, 22(R)-dihydroxycholesterol, 50% inhibition at 51% glycerol | Bos taurus |
Organic Solvent | Comment | Organism |
---|---|---|
Glycerol | induces sigmoidal low-spin response of otherwise high-spin spectrum, weakens adrenodoxin binding, inhibitory effect being substrate dependent | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
enzyme incorporated into phosphatidylcholine vesicles | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
20alpha, 22(R)-dihydroxycholesterol + reduced adrenodoxin + O2 | - |
Bos taurus | ? + oxidized adrenodoxin + H2O | - |
? | |
20alpha-hydroxycholesterol + reduced adrenodoxin + O2 | - |
Bos taurus | pregnenolone + 4-methylpentanal + oxidized adrenodoxin + H2O | - |
? | |
22(R)-hydroxycholesterol + reduced adrenodoxin + O2 | - |
Bos taurus | ? + oxidized adrenodoxin + H2O | - |
? | |
cholesterol + reduced adrenodoxin + O2 | - |
Bos taurus | ? + oxidized adrenodoxin + H2O | - |
? |