Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | genes amh and cyp11b are both upregulated during juvenile ovary-to-testis transformation | Danio rerio |
Cloned (Comment) | Organism |
---|---|
gene cyp11b, sequence comparison and expression analysis | Danio rerio |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Danio rerio | the enzyme is involved in gonadal transformation in the zebrafish, enzyme expression regulation, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Danio rerio | A1XRK1 | gene cyp11b, a protogynous hermaphroditic fish | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Danio rerio | - |
eye | - |
Danio rerio | - |
gonad | during development all zebrafish males first develop a juvenile ovary, that later degenerates and transforms into a testis, the enzyme is involved, but not inducing, in gonadal transformation in the zebrafish, but its localization is not related to the position of degenerating oocytes, overview | Danio rerio | - |
gut | - |
Danio rerio | - |
heart | - |
Danio rerio | - |
kidney | - |
Danio rerio | - |
liver | - |
Danio rerio | - |
additional information | the mRNA of cyp11b is detected in all the adult organs tested | Danio rerio | - |
muscle | higher enzyme expression level | Danio rerio | - |
ovary | - |
Danio rerio | - |
skin | - |
Danio rerio | - |
testis | very high expression level | Danio rerio | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
corticosterone + reduced adrenal ferredoxin + O2 | - |
Danio rerio | 11-deoxycorticosterone + adrenal ferredoxin + ? | - |
? | |
additional information | the enzyme is involved in gonadal transformation in the zebrafish, enzyme expression regulation, overview | Danio rerio | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
11 beta-hydroxylase | - |
Danio rerio |
cyp11beta | - |
Danio rerio |
P45011beta | - |
Danio rerio |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
reduced adrenal ferredoxin | - |
Danio rerio |