Cloned (Comment) | Organism |
---|---|
genes fmo1, fmo2, fmo3, quantitative expression analysis in different tissues, expression in Spodoptera frugiperda Sf9 cells using the baculovirus transfection system | Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
3.6 | - |
methyl p-tolyl sulfide | pH 8.5, FMO1 | Mus musculus | |
10.2 | - |
methyl p-tolyl sulfide | pH 8.5, FMO2 | Mus musculus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Mus musculus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
several strains, overview, genes fmo1, fmo2, fmo3, and fmo5 | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Mus musculus | - |
lung | - |
Mus musculus | - |
additional information | tissue-specific expression of FMO isozymes, quantitative expression analysis, overview | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
methimazole + NADPH + H+ + O2 | FMO1, FMO2, and FMO3 | Mus musculus | ? | - |
? | |
methyl p-tolyl sulfide + NADPH + H+ + O2 | FMO1, FMO2, but poor substrate of FMO3 | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
FMO | - |
Mus musculus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
50 | - |
10 min, elimination of most Fmo1 and Fmo3 activity, while 94% of Fmo2 activity remains | Mus musculus |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.25 | - |
methyl p-tolyl sulfide | pH 8.5, FMO2 | Mus musculus | |
2.9 | - |
methyl p-tolyl sulfide | pH 8.5, FMO1 | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.5 | 9.5 | assay at | Mus musculus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | - |
Mus musculus | |
NADPH | - |
Mus musculus |