Literature summary for 1.14.13.8 extracted from

Bartsch, M.; Gobbato, E.; Bednarek, P.; Debey, S.; Schultze, J.L.; Bautor, J.; Parker, J.E.
Salicylic acid-independent enhanced disease susceptibility1 signaling in Arabidopsis immunity and cell death is regulated by the monooxygenase FMO1 and the Nudix hydrolase NUDT7 (2006), Plant Cell, 18, 1038-1051.

Search for more literature for 1.14.13.8

Cloned(Commentary)

Cloned (Comment)	Organism
whole genome microarrays to examine the EDS1 regulatory node in disease resistance and correlation of FMO1 expression, overview	Arabidopsis thaliana

Protein Variants

Protein Variants	Comment	Organism
additional information	construction of fmo1 defective mutants, FMO1 mutations specifically affects the EDS1 pathway, defects in Arabidopsis fmo1 mutants are not coupled to SA accumulation, reduced pathogen defense, phenotype, analysis of fmo1 and nudt7 mutants alone or in combination with sid2-1, a mutation that severely depletes pathogen-induced salicylic acid production, points to salicylic acid-independent functions of FMO1 and NUDT7 in EDS1-conditioned disease resistance and cell death, overview	Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
additional information	Arabidopsis thaliana	enhanced disease susceptibility1, EDS1, controls defense activation and programmed cell death conditioned by intracellular Toll-related immune receptors that recognize specific pathogen effectors in Arabidopsis thaliana, EDS1 is also needed for basal resistance to invasive pathogens by restricting the progression of disease, EDS1 with phytoalexin-deficient 4, PAD4, regulates accumulation of the phenolic defense molecule salicylic acid, EDS1 is regulated by FMO and the Nudix hydrolase NUDT7	?	-	?

Organism

Organism	UniProt	Comment	Textmining
Arabidopsis thaliana	Q9LMA1	isozyme FMO1	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
additional information	enhanced disease susceptibility1, EDS1, controls defense activation and programmed cell death conditioned by intracellular Toll-related immune receptors that recognize specific pathogen effectors in Arabidopsis thaliana, EDS1 is also needed for basal resistance to invasive pathogens by restricting the progression of disease, EDS1 with phytoalexin-deficient 4, PAD4, regulates accumulation of the phenolic defense molecule salicylic acid, EDS1 is regulated by FMO and the Nudix hydrolase NUDT7	Arabidopsis thaliana	?	-	?

Synonyms

Synonyms	Comment	Organism
monooxygenase FMO1	-	Arabidopsis thaliana

Cofactor

Cofactor	Comment	Organism	Structure
FAD	-	Arabidopsis thaliana
NADPH	-	Arabidopsis thaliana

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)