Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Methimazole | not competitive; oxidation of dimethylaniline | Squalus acanthias | |
thiobenzamide | oxidation of dimethylaniline, competitive | Squalus acanthias | |
trimethylamine | 1 mM, oxidation of dimethylaniline, competitive | Squalus acanthias |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.044 | - |
N,N-Dimethylaniline | - |
Squalus acanthias |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
microsome | - |
Squalus acanthias | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | - |
Western blot, anti-FMO 2 antisera | Squalus acanthias |
50000 | - |
Western blot, anti-FMO 2 antisera | Carcharhinus falciformis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Carcharhinus falciformis | - |
silky shark | - |
Squalus acanthias | - |
dogfish shark | - |
Purification (Comment) | Organism |
---|---|
partial | Carcharhinus falciformis |
Source Tissue | Comment | Organism | Textmining |
---|
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
methimazole + NADPH + O2 | - |
Squalus acanthias | N-methylmethimidazole-2-sulfinic acid + NADP+ + H2O | - |
? | |
N,N-dimethylaniline + NADPH + H+ + O2 | - |
Squalus acanthias | N,N-dimethylaniline N-oxide + NADP+ + H2O | - |
r | |
N,N-dimethylaniline + NADPH + O2 | - |
Squalus acanthias | N,N-dimethylaniline N-oxide + NADP+ + H2O | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
- |
Squalus acanthias |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
15 | 45 | 15°C, 76% loss of activity, 45°C 99% loss of activity | Squalus acanthias |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
9.6 | - |
- |
Squalus acanthias |