Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
54000 | - |
SDS-PAGE, FMO-I | Cavia porcellus |
56000 | - |
SDS-PAGE, FMO-II | Cavia porcellus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Cavia porcellus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
2 forms: FMO-I and FMO-II | Cavia porcellus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Cavia porcellus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.41 | - |
thiobenzamide S-oxidase activity, FMO-II | Cavia porcellus |
0.436 | - |
thiobenzamide S-oxidase activity, FMO-I | Cavia porcellus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
chlorpromazine + NADPH + O2 | - |
Cavia porcellus | ? | - |
? | |
cysteamine + NADPH + O2 | - |
Cavia porcellus | ? | - |
? | |
methamphetamine + NADPH + O2 | - |
Cavia porcellus | ? | - |
? | |
methimazole + NADPH + O2 | - |
Cavia porcellus | N-methylmethimidazole-2-sulfinic acid + NADP+ + H2O | - |
? | |
additional information | specificity of FMO-I and FMO-II | Cavia porcellus | ? | - |
? | |
N,N-dimethylaniline + NADPH + O2 | - |
Cavia porcellus | N,N-dimethylaniline N-oxide + NADP+ + H2O | - |
? | |
phenylthiourea + NADPH + O2 | - |
Cavia porcellus | ? | - |
? | |
thiourea + NADPH + O2 | - |
Cavia porcellus | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 56000, FMO-II, SDS-PAGE | Cavia porcellus |
? | x * 54000, FMO-I, SDS-PAGE | Cavia porcellus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | flavoprotein | Cavia porcellus | |
FAD | 1 FAD per enzyme | Cavia porcellus |