Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Guanidines | stimulate NADPH- and O2-dependent oxidation of tertiary amines and sulfur-containing substrates with alkyl side-chains of less than 5 carbons | Sus scrofa | |
Lipophilic primary alkylamines | stimulate NADPH- and O2-dependent oxidation of tertiary amines and sulfur-containing substrates with alkyl side-chain of less than 5 carbons | Sus scrofa | |
n-octylamine | stimulation of tert-amine oxidation, not sec-amine oxidation | Sus scrofa | |
tertiary amines | self-activation with alkyl side chains of 7 or more | Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
anionic detergents | - |
Sus scrofa | |
fatty acids | - |
Sus scrofa | |
SDS | - |
Sus scrofa | |
stearate | - |
Sus scrofa |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
65000 | - |
8 * 65000, SDS-PAGE | Sus scrofa |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Sus scrofa |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
1.43 | - |
- |
Sus scrofa |
Storage Stability | Organism |
---|---|
-15°C, several months with little or no loss of activity | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
methimazole + NADPH + O2 | - |
Sus scrofa | N-methylmethimidazole-2-sulfinic acid + NADP+ + H2O | - |
? | |
additional information | catalyzes NADPH- and O2-dependent N-oxidation of N-substituted amines and hydrazines and the S-oxidation of thioureylenes and thiols | Sus scrofa | ? | - |
? | |
N,N-dimethylaniline + NADPH + O2 | - |
Sus scrofa | N,N-dimethylaniline N-oxide + NADP+ + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
octamer | 8 * 65000, SDS-PAGE | Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FAD | flavoprotein | Sus scrofa | |
NADH | - |
Sus scrofa | |
NADPH | - |
Sus scrofa |