Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Homo sapiens | - |
additional information | FMO3 is not expressed in HepG2 cells | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
flavin containing monooxygenase 3 | - |
Homo sapiens |
FMO3 | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | no changes in relative FMO3 mRNA levels are observed with 50 nM trichostatin A | additional information |
Homo sapiens | 5-aza-2'-deoxycytidine at 0.001 mM and 0.0025 mM results in 6.6fold and 9.2fold increases in FMO3 mRNA levels, respectively. HNF4alpha transient expression results in a 3.1fold increase in FMO3 mRNA levels. Co-transfection of HepG2 cells with the CCAAT/enhancer-binding protein beta expression vector and the pRNH694 reporter construct results in a dose-dependent increase in FMO3 promoter activity with a maximal 2fold increase using 0.001 mg of expression | up |