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Literature summary for 1.14.11.17 extracted from

  • Elkins, J.M.; Ryle, M.J.; Clifton, I.J.; Dunning Hotopp, J.C.; Lloyd, J.S.; Burzlaff, N.I.; Baldwin, J.E.; Hausinger, R.P.; Roach, P.L.
    X-ray crystal structure of Escherichia coli taurine/alpha-ketoglutarate dioxygenase complexed to ferrous iron and substrates (2002), Biochemistry, 41, 5185-5192.
    View publication on PubMed

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging drop method, inclusion of taurine and 2-oxoglutarate is absolutely required for crystal formation Escherichia coli

Metals/Ions

Metals/Ions Comment Organism Structure
Fe2+ required, essential cofactor Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
taurine + 2-oxoglutarate + O2 Escherichia coli enables the use of taurine as sulfur source sulfite + aminoacetaldehyde + succinate + CO2
-
?

Organism

Organism UniProt Comment Textmining
Escherichia coli P37610
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
additional information Trp128, Trp240, and Trp248 are hydroxylated upon exposure to oxygen Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
taurine + 2-oxoglutarate + O2
-
Escherichia coli sulfite + aminoacetaldehyde + succinate + CO2
-
?
taurine + 2-oxoglutarate + O2 enables the use of taurine as sulfur source Escherichia coli sulfite + aminoacetaldehyde + succinate + CO2
-
?

Subunits

Subunits Comment Organism
dimer crystal structure analysis Escherichia coli

Synonyms

Synonyms Comment Organism
TauD
-
Escherichia coli
taurine/alpha-ketoglutarate dioxygenase
-
Escherichia coli