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Literature summary for 1.13.12.7 extracted from

  • Lang, T.; Goyard, S.; Lebastard, M.; Milon, G.
    Bioluminescent Leishmania expressing luciferase for rapid and high throughput screening of drugs acting on amastigote-harbouring macrophages and for quantitative real-time monitoring of parasitism features in living mice (2005), Cell. Microbiol., 7, 383-392.
    View publication on PubMed

Application

Application Comment Organism
analysis expression of bioluminescent luciferase can be used for rapid and high throughput screening of drugs, e.g. quinolines, acting on Leishmania amastigote-harbouring macrophages and for quantitative real-time monitoring of parasitism features in living mice, overview Photinus pyralis

Cloned(Commentary)

Cloned (Comment) Organism
expression in transfected Leishmania amazonensis strain LV79 amastigotes, transfection by electroporation Photinus pyralis

Organism

Organism UniProt Comment Textmining
Photinus pyralis
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
measuring luminescence of recombinant luciferase in transfected Leishmania amazonensis amostigotes Photinus pyralis

Synonyms

Synonyms Comment Organism
firefly luciferase
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Photinus pyralis
luciferase
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Photinus pyralis