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Literature summary for 1.13.11.31 extracted from
- Expression and regulation of 12/15-lipoxygenases in human primary macrophages (2012), Atherosclerosis, 225, 121-127.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| macrophage | - |
Homo sapiens | - |
| monocyte | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ALOX12 | - |
Homo sapiens |
| Alox15 | - |
Homo sapiens |
| ALOX15B | - |
Homo sapiens |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | expression of ALOX12 remains on the same level during differentiation from monocyte to macrophage | additional information |
| Homo sapiens | an increase of ALOX15B expression during the differentiation of monocytes to macrophages is shown. Stimulation of macrophages with a set of cytokines and with hypoxia reveals that IL-4, IL-13, LPS and hypoxia further increase the ALOX15B mRNA | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | ALOX15B might play a major role in human atherosclerosis | Homo sapiens |
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