Inhibitors | Comment | Organism | Structure |
---|---|---|---|
N-benzyl-N-hydroxy-5-phenylpentanamide | - |
Homo sapiens | |
N-benzyl-N-hydroxy-5-phenylpentanamide | - |
Mus musculus | |
N-benzyl-N-hydroxy-5-phenylpentanamide | - |
Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | the 12-lipoxygenase pathway plays a critical role in angiogenesis | ? | - |
? | |
additional information | Homo sapiens | the 12-lipoxygenase pathway plays a critical role in angiogenesis | ? | - |
? | |
additional information | Rattus norvegicus | the 12-lipoxygenase pathway plays a critical role in angiogenesis | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
endothelial cell | cell line RV-ECT | Rattus norvegicus | - |
endothelial cell | capillary endothelial cell line CD4 | Mus musculus | - |
endothelial cell | umbelical vein endothelial cells and foreskin dermal microvascular endothelial cells | Homo sapiens | - |
prepuce | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
arachidonate + O2 | i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid | Mus musculus | (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate | - |
? | |
arachidonate + O2 | i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid | Homo sapiens | (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate | - |
? | |
arachidonate + O2 | i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid | Rattus norvegicus | (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate | - |
? | |
additional information | the 12-lipoxygenase pathway plays a critical role in angiogenesis | Mus musculus | ? | - |
? | |
additional information | the 12-lipoxygenase pathway plays a critical role in angiogenesis | Homo sapiens | ? | - |
? | |
additional information | the 12-lipoxygenase pathway plays a critical role in angiogenesis | Rattus norvegicus | ? | - |
? |