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Literature summary for 1.13.11.31 extracted from

  • Van der Donk, E.M.M.; Verhagen, J.; Veldink, G.A.; Vliegenhart, J.F.G.
    12-Lipoxygenase from rat basophilic leukemia cells: separation from 5-lipoxygenase and temperature-dependent inactivation by hydroperoxy fatty acid (1991), Biochim. Biophys. Acta, 1081, 135-140.
    View publication on PubMed
Search for more literature for 1.13.11.31

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
 Rattus norvegicus 5829
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
leukemia cell basophilic Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
arachidonate + O2 i.e. 5Z,8Z,11Z,14Z-eicosatetraenoic acid Rattus norvegicus (5Z,8Z,10E,14Z)-(12S)-12-hydroperoxyicosa-5,8,10,14-tetraenoate
-
 ?
linoleic acid + O2
-
 Rattus norvegicus 13(S)-hydroperoxy-9Z,11E-octadecadienoic acid
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
10
-
 cytosolic fraction Rattus norvegicus

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
37
-
 rapid inactivation by the product hydroperoxy fatty acid, at low concentrations, 10-100 nM Rattus norvegicus