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Literature summary for 1.12.7.2 extracted from

  • Welte, C.; Kallnik, V.; Grapp, M.; Bender, G.; Ragsdale, S.; Deppenmeier, U.
    Function of Ech hydrogenase in ferredoxin-dependent, membrane-bound electron transport in Methanosarcina mazei (2010), J. Bacteriol., 192, 674-678.
    View publication on PubMedView publication on EuropePMC

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Methanosarcina mazei 16020
-

Organism

Organism UniProt Comment Textmining
Methanosarcina mazei
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
H2 + oxidized ferredoxin
-
Methanosarcina mazei H+ + reduced ferredoxin
-
?

Subunits

Subunits Comment Organism
hexamer
-
Methanosarcina mazei

Synonyms

Synonyms Comment Organism
Ech hydrogenase
-
Methanosarcina mazei

Cofactor

Cofactor Comment Organism Structure
Ferredoxin
-
Methanosarcina mazei

General Information

General Information Comment Organism
malfunction the Ech hydrogenase deletion mutant shows 50% decreased ferredoxin-dependent membrane-bound electron transport activity, a lower growth rate, and 2fold faster substrate (trimethylamine) consumption compared to the wild type enzyme Methanosarcina mazei