Crystallization (Comment) | Organism |
---|---|
- |
Bos taurus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ag+ | - |
Bos taurus | |
Chloroacetate | - |
Bos taurus | |
iodoacetate | - |
Bos taurus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
21900 | - |
alpha4, 4 * 21900, nucleotide sequence, SDS-PAGE | Bos taurus |
75000 | 85500 | gel filtration | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + ROOH | Mammalia | cumene hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | Bos taurus | cumene hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | Mammalia | ethyl hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | Bos taurus | ethyl hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | Bos taurus | cholesterol 7beta-hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | Mammalia | peroxidized DNA | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | Bos taurus | peroxidized DNA | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | Bos taurus | pregnenolone 17alpha-hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | Mammalia | thymine hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | Bos taurus | thymine hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | Mammalia | highly specific for glutathione | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | Bos taurus | highly specific for glutathione | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | Mammalia | linoleic acid hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | Bos taurus | linoleic acid hydroperoxide | glutathione disulfide + ROH + H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
- |
- |
Mammalia | - |
- |
- |
no activity in plants | - |
- |
- |
Oxidation Stability | Organism |
---|---|
autooxidation, reactivation by glutathione | Mammalia |
autooxidation, reactivation by glutathione | Bos taurus |
Purification (Comment) | Organism |
---|---|
- |
Bos taurus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + ROOH | cumene hydroperoxide | Mammalia | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | cumene hydroperoxide | Bos taurus | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | ethyl hydroperoxide | Mammalia | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | ethyl hydroperoxide | Bos taurus | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | cholesterol 7beta-hydroperoxide | Bos taurus | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | peroxidized DNA | Mammalia | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | peroxidized DNA | Bos taurus | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | pregnenolone 17alpha-hydroperoxide | Bos taurus | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | thymine hydroperoxide | Mammalia | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | thymine hydroperoxide | Bos taurus | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | highly specific for glutathione | Mammalia | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | highly specific for glutathione | Bos taurus | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | linoleic acid hydroperoxide | Mammalia | glutathione disulfide + ROH + H2O | - |
? | |
glutathione + ROOH | linoleic acid hydroperoxide | Bos taurus | glutathione disulfide + ROH + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
homotetramer | - |
Mammalia |
homotetramer | alpha4, 4 * 21900, nucleotide sequence, SDS-PAGE | Bos taurus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
42 | - |
- |
Bos taurus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.8 | - |
- |
Bos taurus |
pH Stability | pH Stability Maximum | Comment | Organism |
---|---|---|---|
7 | 10 | - |
Bos taurus |