Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 1.11.1.6 extracted from

  • Wang, M.; Wang, L.; Zhou, Z.; Gao, Y.; Wang, L.; Shi, X.; Gai, Y.; Mu, C.; Song, L.
    The molecular characterization of a catalase from Chinese mitten crab Eriocheir sinensis (2013), Int. J. Immunogenet., 40, 230-240.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
DNA and amino acid sequence determination and analysis, phylogenetic analyis Eriocheir sinensis

Localization

Localization Comment Organism GeneOntology No. Textmining
peroxisome
-
Eriocheir sinensis 5777
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
58860
-
4x * 58860, sequence calculation Eriocheir sinensis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2 H2O2 Eriocheir sinensis
-
O2 + 2 H2O
-
?

Organism

Organism UniProt Comment Textmining
Eriocheir sinensis
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
gill
-
Eriocheir sinensis
-
gonad
-
Eriocheir sinensis
-
heart
-
Eriocheir sinensis
-
hemocyte
-
Eriocheir sinensis
-
hepatopancreas high expression level Eriocheir sinensis
-
additional information constitutive epression, tissue expression analysis, overview Eriocheir sinensis
-
muscle
-
Eriocheir sinensis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2 H2O2
-
Eriocheir sinensis O2 + 2 H2O
-
?

Subunits

Subunits Comment Organism
homotetramer 4x * 58860, sequence calculation Eriocheir sinensis

Synonyms

Synonyms Comment Organism
CAT
-
Eriocheir sinensis

Cofactor

Cofactor Comment Organism Structure
heme EsCAT contains a proximal heme-ligand signature motif, 350RLFSYNDTH358. Each monomer contains a single heme Eriocheir sinensis
NADPH Each monomer contains a NADPH bound on the surface of each monomer by 12 amino acid residues and protects the enzyme from oxidation by its substrate, H2O2 Eriocheir sinensis

pI Value

Organism Comment pI Value Maximum pI Value
Eriocheir sinensis sequence calculation
-
6.9

General Information

General Information Comment Organism
evolution EsCAT contains a highly conserved proximal active-site signature motif (60FDRERIPERVVHAKGAL76) and a proximal heme-ligand signature motif (350RLFSYNDTH358) and exhibits high similarity with other reported CATs Eriocheir sinensis
physiological function catalase is an antioxidant enzyme and plays a significant role in the protection against oxidative stress by reducing hydrogen peroxide Eriocheir sinensis