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Literature summary for 1.11.1.6 extracted from

  • Hoeflich, A.; Fettscher, O.; Preta, G.; Lahm, H.; Kolb, H.J.; Wolf, E.; Weber, M.M.
    Increased activity of catalase in tumor cells overexpressing IGFBP-2 (2003), Horm. Metab. Res., 35, 816-821.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information increased activity of catalase in tumor cells recombinantly overexpressing IGFBP-2 probably mediated through IGF-independent mechanisms Mus musculus
additional information increased activity of catalase in tumor cells recombinantly overexpressing IGFBP-2 probably mediated through IGF-independent mechanisms Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
293 cell epithelial cell Homo sapiens
-
adrenocortical carcinoma cell Y-1 cell, increased activity of catalase in tumor cells recombinantly overexpressing IGFBP-2 probably mediated through IGF-independent mechanisms Mus musculus
-
Caco-2 cell adrenocortical tumor cell, increased activity of catalase in tumor cells recombinantly overexpressing IGFBP-2 probably mediated through IGF-independent mechanisms Mus musculus
-
Caco-2 cell colon tumor cell, increased activity of catalase in tumor cells recombinantly overexpressing IGFBP-2 probably mediated through IGF-independent mechanisms Homo sapiens
-
colonic cancer cell Caco-2 cell, increased activity of catalase in tumor cells recombinantly overexpressing IGFBP-2 probably mediated through IGF-independent mechanisms Homo sapiens
-
epithelial cell 293 cell Homo sapiens
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
1.5
-
about, cell lysates of wild-type Caco-2 cells Homo sapiens
3.5 4.5 about, cell lysates of wild-type Y-1 cells Mus musculus
6
-
about, cell lysates of Caco-2 cells recombinantly overexpressing IGFBP-2 Homo sapiens
8
-
about, cell lysates of Y-1 cells recombinantly overexpressing IGFBP-2 Mus musculus
77.5
-
about, cell lysates of wild-type and recombinantly IGFBP-2-overexpressing 293 cells Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
H2O2
-
Mus musculus O2 + H2O
-
?
H2O2
-
Homo sapiens O2 + H2O
-
?