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Literature summary for 1.11.1.6 extracted from

  • Aebi, H.E.
    Catalase. Hydrogen-peroxide:hydrogen-peroxide oxidoreductase E.C. 1.11.1.6 (1983), Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. ), 3, 373-386.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
3-amino-1H-1,2,4-triazole exclusive in vivo inhibitor Homo sapiens
acetic acid in vitro inhibitor Homo sapiens
ascorbate in vitro inhibitor Homo sapiens
BrCN acting in vitro Homo sapiens
ethanol in vitro inhibitor Homo sapiens
F- in vitro inhibitor Homo sapiens
formic acid in vitro inhibitor Homo sapiens
hydroxylamine in vitro inhibitor Homo sapiens
KCN acting in vitro Homo sapiens
methanol in vitro inhibitor Homo sapiens
NaN3 acting in vitro Homo sapiens
nitrite in vitro inhibitor Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm erythrocytes Homo sapiens 5737
-
mitochondrion mainly in liver and kidney Homo sapiens 5739
-
peroxisome mainly in liver and kidney Homo sapiens 5777
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
H2O2 Homo sapiens abnormal reaction kinetics O2 + H2O
-
?
H2O2 Homo sapiens involved in acatalasemia O2 + H2O
-
?
H2O2 Homo sapiens regulator of H2O2-levels or protective function for hemoglobin or other SH-proteins O2 + H2O
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
erythrocyte
-
Homo sapiens
-
kidney
-
Homo sapiens
-
liver
-
Homo sapiens
-

Storage Stability

Storage Stability Organism
2°C, intact erythrocytes or concentrated hemolysates, 6 days Homo sapiens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ethanol + H2O2
-
Homo sapiens acetaldehyde + ?
-
?
formic acid + H2O2
-
Homo sapiens ?
-
?
H2O2 abnormal reaction kinetics Homo sapiens O2 + H2O
-
?
H2O2 involved in acatalasemia Homo sapiens O2 + H2O
-
?
H2O2 regulator of H2O2-levels or protective function for hemoglobin or other SH-proteins Homo sapiens O2 + H2O
-
?
methanol + H2O2
-
Homo sapiens formaldehyde + ?
-
?

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
-
37
-
Homo sapiens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.8 7.5
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
heme
-
Homo sapiens