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Literature summary for 1.11.1.5 extracted from

  • Hays Putnam, A.M.; Lee, Y.T.; Goodin, D.B.
    Replacement of an electron transfer pathway in cytochrome c peroxidase with a surrogate peptide (2009), Biochemistry, 48, 1-3.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Saccharomyces cerevisiae

Crystallization (Commentary)

Crystallization (Comment) Organism
protein channel mutant with surrogate protein (N-benzimidazole-propionic acid)-Gly-Ala-Ala (BzGAA), vapor diffusion, 200 mM KPi, 25% MPD, pH 6.0, temperature 282K, space group P212121, resolution 1.6 A Saccharomyces cerevisiae

Protein Variants

Protein Variants Comment Organism
additional information variant of cytochrome c peroxidase in which the proposed electron transfer pathway is excised from the structure, leaving a water filled channel in its place Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
cytochrome c + H2O2 Saccharomyces cerevisiae
-
?
-
?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae P00431 bakerย’s yeast
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cytochrome c + H2O2
-
Saccharomyces cerevisiae ?
-
?
additional information investigation of an engineered channel mutant with the surrogate peptide (N-benzimidazole-propionic acid)-Gly-Ala-Ala (BzGAA), complete loss of functional activity in the BzGAA/ET channel mutant strongly supports proposals that the Trp-191 radical intermediate is required for efficient turnover of cyt c via the proposed ET pathway Saccharomyces cerevisiae ?
-
?

Synonyms

Synonyms Comment Organism
CCP
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Saccharomyces cerevisiae
cytochrome c peroxidase
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Saccharomyces cerevisiae

General Information

General Information Comment Organism
physiological function electron transfer Saccharomyces cerevisiae