Inhibitors | Comment | Organism | Structure |
---|---|---|---|
iodoacetate | 2 mM, complete inhibition | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
membrane | - |
Homo sapiens | 16020 | - |
mitochondrion | - |
Homo sapiens | 5739 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
20000 | - |
1 * 20000, non-mitochondrial S-form of the enzyme | Homo sapiens |
23000 | - |
1 * 23000, mitochondrial L-form of the enzyme | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood platelet | resting blood platelet | Homo sapiens | - |
erythrocyte | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0038 | - |
crude platelet homogenate | Homo sapiens |
0.0048 | - |
cytosolic fraction | Homo sapiens |
0.006 | - |
mitochondrial fraction | Homo sapiens |
0.0096 | - |
membrane fraction | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glutathione + L-alpha-phosphatidylcholine hydroperoxide | - |
Homo sapiens | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
monomer | 1 * 20000, non-mitochondrial S-form of the enzyme | Homo sapiens |
monomer | 1 * 23000, mitochondrial L-form of the enzyme | Homo sapiens |
Synonyms | Comment | Organism |
---|---|---|
GPx-4 | - |
Homo sapiens |