Activating Compound | Comment | Organism | Structure |
---|---|---|---|
arsenate | increasing activity up to 0.1 M, inhibition of ferricyanide-linked assay above 0.1 M | Sus scrofa | |
phosphate | increasing activity up to 0.1 M, inhibition of ferricyanide-linked assay above 0.1 M | Sus scrofa |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
acetate | - |
Sus scrofa | |
arsenate | inhibition of glycolate-ferricyanide or glyoxylate-ferricyanide assay above 0.1 M | Sus scrofa | |
Butyrate | - |
Sus scrofa | |
glycolate | inhibition above 1.7 mM | Sus scrofa | |
Heptanoate | - |
Sus scrofa | |
hexanoate | - |
Sus scrofa | |
malonate | - |
Sus scrofa | |
oxalate | - |
Sus scrofa | |
phosphate | inhibition of glycolate-ferricyanide or glyoxylate-ferricyanide assay above 0.1 M | Sus scrofa | |
propionate | - |
Sus scrofa | |
succinate | - |
Sus scrofa | |
valerate | - |
Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.28 | - |
dichlorophenolindophenol | cosubstrate: glycolate | Sus scrofa | |
0.42 | - |
glycolate | cosubstrate: 2,6-dichlorophenolindophenol | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
glycolate + O2 | Sus scrofa | - |
glyoxylate + H2O2 | - |
? | |
glyoxylate + O2 | Sus scrofa | - |
? + H2O2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
pig | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Sus scrofa | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
glycolate + 2,6-dichlorophenolindophenol | - |
Sus scrofa | glyoxylate + reduced 2,6-dichlorophenolindophenol | - |
? | |
glycolate + ferricyanide | - |
Sus scrofa | glyoxylate + ferrocyanide | - |
? | |
glycolate + O2 | - |
Sus scrofa | glyoxylate + H2O2 | - |
? | |
glyoxylate + 2,6-dichlorophenolindophenol | - |
Sus scrofa | ? + reduced 2,6-dichlorophenolindophenol | - |
? | |
glyoxylate + ferricyanide | - |
Sus scrofa | ? + ferrocyanide | - |
? | |
glyoxylate + O2 | - |
Sus scrofa | ? + H2O2 | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
FMN | - |
Sus scrofa |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | straight-chain monocarboxylic acids are non-competitive inhibitors with either glycolate or glyoxylate as substrates, dicarboxylic acids are competitive inhibitors with glycolate as substrate, but non-competitive inhibitors for glyoxylate as substrate | Sus scrofa | |
0.092 | - |
Heptanoate | non-competitive, glycolate oxidation | Sus scrofa | |
0.3 | - |
hexanoate | non-competitive, glycolate oxidation | Sus scrofa | |
0.44 | - |
oxalate | competitive, glycolate oxidation, non-competitive for glyoxylate oxidation | Sus scrofa | |
1.2 | - |
valerate | non-competitive, glyoxylate reduction | Sus scrofa | |
1.3 | - |
valerate | non-competitive, glycolate oxidation | Sus scrofa | |
3.6 | - |
Butyrate | non-competitive, glycolate oxidation | Sus scrofa | |
8.2 | - |
malonate | non-competitive, glyoxylate reduction | Sus scrofa | |
9.2 | - |
malonate | competitive, glycolate oxidation | Sus scrofa | |
9.5 | - |
propionate | non-competitive, glycolate oxidation | Sus scrofa | |
14 | - |
succinate | competitive, glycolate oxidation | Sus scrofa | |
17 | - |
propionate | non-competitive, glyoxylate reduction | Sus scrofa | |
37 | - |
acetate | non-competitive, glycolate oxidation | Sus scrofa | |
48 | - |
acetate | non-competitive, glyoxylate reduction | Sus scrofa |